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Semaglutid, GLP-1 reseptrlerini aktive eden (GLP-1 agonisti) bir etken maddedir

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On top of that, early research suggests that GLP-1s may affect certain serotonin receptors, including one called 5-HT2C

Furthermore, in relation to the anti-inflammatory activities of GLP-1 RAs, an apparent sex effect is observed in an animal model of food restriction of the mother

Notably, current evidence regarding the impact of GLP-1 RA on HF primarily originates from placebo-controlled CVOTs conducted in populations with T2DM or obesity characterized by significant cardiovascular risk factors or established cardiovascular disease

How does this align with the medical literature and what I have seen in my 12 years of prescribing these medications for people with diabetes