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This trend aligns with national dispensing patterns, where a study reported a nearly 600% increase in GLP-1 RA prescription fills among adolescents and young adults from 2020 to 2023 ( 9 ) and our own research, which has shown that GLP-1 RAs now make up over 5% of all prescriptions prescribed

In contrast, participants without the risk allele showed correlations in the opposite direction (Karra et al., 2013)

Researchers found that the safety profiles of both drugs were generally consistent with the GLP-1 receptor agonist class

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