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It is unknown to what extent these risks in prediabetes remain after accounting for progression to diabetes

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Mechanistically, multi-omics analyses of cardiac and hepatic tissues revealed that semaglutide exerted these benefits by improving cardiac metabolism, interfering with pro-fibrotic and pro-hypertrophic signals, and by reducing systemic inflammation

That means: If you have diabetes, getting your blood sugar and overall health optimized before pregnancy is crucial
