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Beyond its direct impact on the cardiovascular system, hypertension is a critical determinant of cognitive health and a significant risk factor for cognitive impairment, including vascular dementia and Alzheimers disease

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Despite the absence of adverse cardiovascular effects has been confirmed, this benefit was not verified in an integrated analysis of 12 controlled, randomized, short-term clinical trials (12-52 weeks) comparing exenatide with placebo or insulin [72]

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