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This design yields a ~1-week half-life while preserving high affinity and selectivity for GLP-1R

The recombinant peptide also greatly improved the oral glucose tolerance test of mice, exerted a positive glucoregulatory effect, and most notably had a glucose lowering effect for as long as 16.7 hours in mice altered to create a type 2 diabetic condition and exerted a positive glucoregulatory effect in db/db mice

The day you take a GLP-1 injection matters less than consistency, meal timing, and individual biomarker response