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However, the studies often take a broad landscape, lacking a detailed analysis of the specific roles and limitations of GLP-1RAs across different pain conditions

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In humans, GLP-1Rs are found in a variety of tissues, including pancreatic islets, the lungs, the kidneys, the gastrointestinal tract, the central nervous system, the vagus nerve, endothelial cells and smooth muscle cells, as well as in atrial and ventricular cardiomyocytes

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Because they strongly affect appetite, digestion, and blood sugar, careful management with a healthcare professional is essential

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