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GLP-1 receptor agonists (GLP-1 RAs) such as semaglutide and tirzepatide have rapidly become some of the most transformative therapies in modern medicine
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Divergence across payer type matters: Commercial patients adopt GLP1s earlier and often remain on monotherapy, while Medicare patients face stricter controls and higher comorbidity burdens
Costco, Hims & Hers, and several others entered the weight loss business this year, offering branded and off-brand products
