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This doesnt happen to everyone, but its something people have started to notice more

Endocrinology 158:41394151

Ensure you stay nourished despite a reduced appetite

Isotretinoin can cause significant fatigue and muscle soreness

Overexercising Consistently pushing your body too far during workouts or exercising too often can cause flu-like symptoms, like persistent muscle soreness and fatigue, notes Cleveland Clinic

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