mechanism of action of glp-1 receptor agonist Agonists For Obesity In Non-Diabetic Patients: Game Changer Or Overhyped? A Critical Analysis GlobalRPH GLP-1 Receptor Agonists as Treatments

2 Table 1 List of Clinical Trials Evaluating the Cardiovascular Efficacy and Safety of GLP-1 RAs GLP-1 RA, glucagon-like peptide-1 receptor agonist

doi: 10.1002/hipo.20964 43 DiseaseG

However, a randomized controlled trial by Berro et al

Methods A MEDLINE search, limited to human clinical trials and using the search criteria GLP-1RA or DPP-4 inhibitor, identified seven head-to-head studies and one relevant post hoc analysis (all a GLP-1RA vs

10.7326/m17-2786

Results showed that tirzepatide reduced the odds for all observed cardiometabolic abnormalities, including a 34% reduction in odds for decreased HDL-C, 72% reduction for MetS