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Semaglutide (STEP 1 trial): Participants lost an average of 14.9% of body weight over 68 weeks at the 2.4 mg dose, compared to 2.4% with placebo

Demand for Innovation: An overwhelming 80% of GLP-1 users express interest in trying frozen food products specifically designed to align with their dietary needs

To achieve the enrollment target for the substudy (approximately 100 participants), the main study was overenrolled ( n = 338 versus planned n = 300)

van Campen, C

In mouse and human islets, the insulinotropic effect of dihydrotestosterone depends on GLP-1R activation, and dihydrotestosterone amplifies the incretin effect of GLP-1 (48)

While these effects arise through different mechanisms, their combination may theoretically increase overall gastrointestinal discomfort in some individuals