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Given the lack of individual preclinical models of PCOS that recapitulate all the metabolic, endocrine, and gonadal traits of the clinical syndrome, pharmacological testing was conducted in parallel in these two PCOS models, which are among the most reliable to mimic the metabolic and gonadal phenotype of women with PCOS 36,37 , capturing also the heterogeneity of this condition 38

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DUAL V Investigators

Self-harm emergencies after bariatric surgery: a Population-Based Cohort Study

As the new obesity pharmacotherapies will lead up to 1525% mean WL, intensive lifestyle interventions may provide small additional WL benefit to these treatments [11, 106]
