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- 71 pounds (from an average starting weight of 248)

Abstract The development oftirzepatide, a first in class dual glucose dependent insulinotropic polypeptide andglucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management oftype 2 diabetesandobesity

IntroductionGlucagon-like peptide-1 receptor agonists (GLP-1 RA) are novel agents with proven cardiovascular (CV) benefits