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GLP-1 receptor activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, reduces appetite signaling, and slows gastric emptying in research models GIP receptor activation potentiates insulin secretion in a glucose-dependent manner, modulates adipose tissue metabolism, and contributes to energy balance regulation in preclinical studies The dual incretin mechanism produces additive and potentially synergistic effects on insulin secretion and metabolic regulation compared to GLP-1 receptor activation alone

10.1111/jgh.16340 144 WangC.LiQ.WangW.GuoL.GuoC.SunY.et al (2015)

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Plan for monitoring: Regular follow-ups are essential to adjust dosing, manage side effects, and track progress

Many prebiotic formulas contain only one or two fiber sources

Food strategies remain the same: smaller, softer, earlier meals when symptoms flare