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Together with Daniel Drucker's paper it shows that neither Semaglutide nor Tirzepatide are good drugs to treat CNS diseases, as they do not cross the blood-brain barrier in meaningful quantities

My advice to them is to try to focus on doing the right things eating healthier, exercising and not weight

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[DOI] [PMC free article] [PubMed] [Google Scholar] Han J

[1] [4] Phase 2 trials are designed to assess safety and preliminary efficacy in relatively controlled conditions

Treatment of clozapine-associated obesity and diabetes with exenatide in adults with schizophrenia: a randomized controlled trial (CODEX)
