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Muscle loss with GLP-1RAs is probably proportional to the extent of weight loss, and resistance exercise with adequate protein intake is recommended to preserve muscle mass and function

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Essentially, by amplifying its effects: They signal the brain to increase satiety and decrease appetite, stimulate the pancreas to increase insulin secretion and reduce glucagon secretion, which in turn lowers blood glucose levels and slows down gastric emptying in the gut, making you feel full longer, Dr