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Indirect evidence showed overall superiority over DPP-4 inhibitors, which appears to be a class effect.16,17 However, superiority between GLP-1 RAs and SGLT2 inhibitors varies across different outcomes

Another long-acting GLP-1RA, semaglutide, was evaluated in a 68-week, randomized, placebo-controlled trial across 61 sites in 11 countries [52]

It is important to note that GLP-1 receptor agonists are not FDA-approved specifically for the treatment of MASLD or MASH, though they may be used off-label in appropriate patients

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(iii) Were original research, reviews, or clinical studies published in English