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One key distinction she highlighted is that tirzepatide acts on two hormone pathways, GLP-1 and GIP, which may make it more effective for some people in terms of fat loss, metabolism, and insulin resistance

Compounded GLP 1 and Dual GIP/GLP 1 Receptor Agonists: A Statement from the American Diabetes Association

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Medications from these distinct classes of pharmaceutical agents may be used as treatment by themselves (monotherapy) or in a combination of 2 or more drugs from multiple classes with different mechanisms of action