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As Mainland China emerges as a key centre for innovation in GLP-1 therapies, multinational manufacturers will compete

The effect of GLP-1R agonists on the medical triad of obesity, diabetes, and cancer
In a seminal study by Day et al., 48 several co-agonists with different GLP-1-to-GCG receptor ratios were investigated in murine models and the optimal balance was suggested to be a co-agonist with equal potency on both receptors

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The evidence from the patient's medical history, the normalization of liver enzymes upon drug discontinuation, and the reexposure to the drug strongly suggest a causal relationship between semaglutide and liver injury

Whilst IBD is not caused by Ozempic, patients with undiagnosed IBD may coincidentally be prescribed the medication