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Stimulating the celiac branch of the vagus nerve in rats (Rocca & Brubaker, 1999), or administration of muscarinic receptor agonists to mimic parasympathetic activity in primary Lcell cultures (Anini et al., 2002

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2017;120:e723

Reports that DPP-4 may be associated with glucagon in the secretory granules of the pancreatic -cell first emerged in 1993, when positive staining in pig islets was shown using immunohistochemical and enzyme histochemical techniques (96), but the pancreatic localization of DPP-4 has also been unequivocally demonstrated more recently using molecular biological techniques (9799)