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I was skeptical at first, but the Berberine Patch really helps keep my appetite in check

Adkin DA, Davis SS, Sparrow RA, Huckle PD, Phillips AJ, Wilding IR

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A 5mg dose is 50 units

How GLP-1 Agonists Influence the Gut Microbiome: Evidence vs Real-World Diet Patterns What Preclinical Models Suggest About GLP-1 RAs and Microbial Diversity A publication examining the effects of GLP-1 RAs on the gut microbiome, primarily in murine models, reports beneficial shifts in microbial composition

It can also be easier for insurance companies to cover bariatric surgery due to it being a one-time, permanent solution for weight loss, rather than an ongoing medication