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More recent data from non-diabetic obese populations (the STEP trials) showed similar cardiovascular safety profiles, with no increase in serious cardiac adverse events

Variants in GLP1R, GIPR, FTO, and MC4R influence how your body responds to GLP-1 agonists like semaglutide

This includes women of child-bearing age

However, this proportion should be interpreted with caution, as spontaneous reporting systems are affected by reporting bias, with serious events more likely to be reported

However, your rheumatologist and weight loss provider should communicate about your full medication list, baseline nutrition status, and kidney function before starting semaglutide

Side effects include fatigue, dizziness, nausea and vomiting