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Starting both at once can overwhelm the body
These are dose-dependent (more common at higher doses) and tend to occur during the dose-escalation phase

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GRP stimulation of GLP-1 secretion has also been demonstrated for rat L-cell cultures and in preparations of rat ileum [323,335]

Tirzepatide (Mounjaro) may be used as part of a medically supervised weight loss plan when appropriate

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