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Human No studies regarding the use of SGLT2 inhibitors during lactation in humans were found

GLP-1 receptor agonist therapy has been associated with increased risk of gallbladder and biliary diseases including cholelithiasis and cholecystitis

189,190 In addition, the mitochondrial PGC-1 signaling pathway is also the mechanism of GLP-1 RA to protect neurons from tau hyperphosphorylation, indicating that mitochondrial dysregulation has crosstalk with tau pathology

The New England Journal of Medicine , 10.1056/NEJMoa2511774
TripleHormone-Receptor Agonist Retatrutide for Obesity a Phase 2 Trial

Buysschaert M, Baeck M, Preumont V, Marot L, Hendrickx E, Van Belle A, et al
