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Starting a GLP-1 drug was linked with a 14% overall reduced risk of new substance use disorders and a lower risk of harm for those with existing use disorders

Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes

Nausea is particularly likely to resolve

The logic is that GH-axis compounds are not dose-linear in a helpful way past a point: once the pulse is being driven hard, adding drug mostly buys more IGF-1 exposure, more fluid retention and more glucose disturbance rather than proportionally more benefit

If an injectable compounded product is used after the BUD, there are two major concerns: The concentration of the active ingredient may be less than labeled

Not surprisingly, people who have Type 2 diabetes, as well as those with higher incomes and fewer side effects, are more likely to stay on GLP-1s
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