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Conclusions GLP-1 RAs are effective and safe for treating SICR and WGR after bariatric surgery

It is also a knowledge gap

PMID: 23771206

10,11 Regarding IOP-lowering mechanisms, GLP-1RAs have been shown to inhibit sodium-potassium ATPase in the choroid plexus, decreasing cerebrospinal fluid secretion and lowering intracranial pressure

DPP-4 inhibitors do not have significant effects on GI motility or appetite that are observed with more efficacious (DPP-4 resistant) GLP-1 agonists

A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Overweight: A Randomized, Double-Blind, Placebo-Controlled Trial (TRIUMPH-1)