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Here's some insight into Metformin and GLP-1 blockers, as discussed on the Huberman Lab

In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

It can literally help your body become a Fat Melter

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While existing GLP-1 medications have shown greater weight loss than Lillys oral medication, this option targets both weight loss and type 2 diabetes in patients.