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"The transition phase decides if weight maintenance works or if weight regain creeps in

This is the only weight loss medication that works in the gut rather than the brain

In late-stage trials, people taking orforglipron lost an average of about 12% of their body weight over roughly 72 weeks , and head-to-head studies suggest it may outperform standard oral semaglutide tablets (Rybelsus) in both weight loss and blood sugar control

The most important factor is adherencechoosing a time that fits naturally into daily routines maximises treatment compliance and therapeutic benefit

Monitoring of patients on long-term glucocorticoid therapy

While these are not directly linked to kidney damage, dehydration (from nausea, vomiting or diarrhea) can worsen kidney function in some individuals