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In this small study, nausea was very common and one patient withdrew due to diarrhea

Peripheral mechanisms 12 regulate appetite by monitoring the stomach's actions, such as how quickly it empties, which helps signal to the brain when we're full

This comes from animal studies and was not replicated during placebo-controlled clinical trials

Missing even one suggests waiting another one to two weeks

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Factors influencing response include baseline body weight, adherence to therapy, dietary quality, physical activity levels, sleep patterns, and metabolic factors