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The phase 2, double-blind trial (IMPACT, NCT05989711) is ongoing

[DOI] [PubMed] [Google Scholar] 41.Bird J.K., Troesch B., Warnke I., Calder P.C

Demonstrating a direct, weight-independent hepatic effectparticularly mediated through LSECsadds an entirely new layer of biological plausibility and therapeutic relevance
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Dose escalations: Each time the dose increases, GI symptoms may briefly return

Management of hyperglycaemia in type 2 diabetes, 2018
