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Some patients benefit from a seasonal or as-needed approach rather than year-round continuous therapy

doi: 10.1007/S11606-021-07105-9

This study directly tested that hypothesis

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According to the MHRA/EMC SmPC, these include nausea (occurring in approximately 44% of patients in clinical trials), vomiting, diarrhoea, constipation, and abdominal discomfort

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