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Can we improve the quality of weight loss by augmenting fat mass loss while preserving lean mass

However, any loss of lean mass matters because it can affect physical function, fracture risk and how well the body maintains weight and metabolic health over time

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These factors, combined with robust clinical evidence demonstrating efficacy in glycemic control and weight management, ensure North America retains the largest market share for GLP-1 receptor agonists globally

doi: 10.2174/1570159X18666200528142429 31 AlberdiEWyssenbachAAlberdiMSnchez-GmezMVCavaliereFRodrguezJJet al

GRADE acknowledges that evidence quality is a continuum