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published a comprehensive review on the use of GLP-1 RAs in plastic surgery, focusing for the first time primarily on their potential benefits and practical considerations in reconstructive procedures [96]

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This removal of feedback inhibition causes the hypothalamus to ramp up GnRH output, prompting the pituitary to secrete more: Luteinizing hormone (LH) stimulates testosterone production Follicle-stimulating hormone (FSH) supports sperm production This mechanism is central to its role in PCT protocols and male fertility treatment