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Diabetes Care 44 , 13851392 (2021)

Each meal should contain protein, healthy fat, and low-glycemic carbohydrates

With GLP-1s and other therapies, mild side effects such as nausea, appetite changes, or temporary injection-site irritation are possible

Interestingly, these effects could be partially blocked by co-administration of the GLP-1R antagonist exendin 939, and completely abrogated by surgical vagotomy [97] - further reinforcing the importance of central GLP-1R activity, and its influence on hepatic lipid metabolism

This extended patent protection increases the potential to lengthen the market monopoly, depending on litigation and settlement terms

Patient communities are increasingly organizing around tirzepatide medications