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(2) Obesity with BMI 27 kg/m plus hypertension, dyslipidemia, or type 2 diabetes and two or more obesity-related conditions, OR BMI 35 kg/m after diet and exercise therapy proves insufficient

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A significant reduction in pro-inflammatory molecules, including C-reactive protein (CRP), TNF- , and IL-6, was observed, indicating the inhibition of inflammatory pathways, likely at the level of immune system cells and adipocytes signaling

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