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What began as an unexpected observation and side effect of some medications converged with decades of addiction neuroscience: GLP-1 receptor agonist medications like Ozempic apparently reduce alcohol craving, drinking intensity, and relapses

Semaglutide, a once-weekly human GLP-1 analog, does not reduce the bioavailability of the combined oral contraceptive, ethinylestradiol/levonorgestrel

Moreover, some benefits on clinical and metabolic features of PCOS may not have fully emerged due to the low or medium doses employed in the vast majority of the current studies

Mann JFE, Orsted DD, Brown-Frandsen K, et al

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Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation