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In clinical trials, around 10 to 15 percent of the people who take the drugs are considered non-responders because they did not lose at least 5 percent of their body weight.

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Consumers would be spending in other categories, though, so the household microeconomics of the GLP-1s could increase demand for new clothing, gym memberships, and perhaps even tourism if the individual feels more mobile to travel

Even though it is less consumed, guarana (Paullinia cupana), native to the Amazon rainforest, contains one of the highest natural concentrations of caffeine (2.5% to 8.0% in dry weight) with a chemical profile also rich in phenolic compounds like theobromine, catechins and tannins.2 The tannins help to slow the release of caffeine into the bloodstream, resulting in a more prolonged stimulatory effect.3 This unique pharmacokinetic behavior has led to the widespread incorporation of guarana extract into energy drinks and fatigue-reducing supplements
