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Several clinical trials and post-hoc analyses have examined this question, with consistent findings

doi:10.1016/j.trsl.2021.06.001

Mild redness or irritation at the injection site, temporary headache, or feeling tired after the first few doses typically resolving within days

Extensive research and real-world experience show that GLP-1 injections are generally safe and well-tolerated for long-term use

In clinical trials, the results are modest but real

"Ro's platform makes it easy for patients or providers to connect, enabling patients to ask a question, report a side effect or share progress with a provider any time they need," Manalac said in an emailed statement
