glp 1 side effects mood swings How GLP-1 Weight-Loss Drugs Affect Appetite, Mood, and Behavior Managing Side Effects of GLP-1

When researchers used erythromycin (a prokinetic) to override the effects on stomach emptying, GLP-1's ability to lower glucose dropped [3]

Preclinical research suggests GLP-1 receptor activation may reduce neuroinflammation, decrease amyloid-beta accumulation, enhance synaptic plasticity, and improve brain glucose metabolism

Like all medications, GLP-1 treatments can have side effects

Journal reference: Johnson B, Milstead M, Thomas O, et al

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Trends Endocrinol Metab 22:2433 Tiano JP, Delghingaro-Augusto V, Le May C et al (2011) Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes