retatrutide phase 2 obesity nejm 2023 jastreboff Half-Life & Pharmacokinetics: 6-Day Decay Curve Novel strategies for medical management
Description
Dual and triple agonist therapies currently in development may expand the number of future pharmacotherapy options
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Alipanahi, B., Delong, A., Weirauch, M
Early weight loss includes significant water as glycogen stores deplete and sodium intake typically decreases
Protein intake becomes especially important on GLP-1 therapy because significant weight loss can include lean muscle mass if protein intake is inadequate
doi: 10.1016/j.molmet.2019.09.010
