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doi:10.2337/dc22-1148 Dore DD, Seeger JD, Chan KA

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The combined effect is greater than either lever alone, which is why 15 mg of tirzepatide produces weight loss that 2.4 mg of semaglutide cannot match

The Weight-loss effect of GLP-1RAs Glucagon-Like Peptide-1 receptor agonists in Non-diabetic individuals with overweight or obesity: A systematic review with Meta-Analysis and trial sequential analysis of randomized controlled trials