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Terns Pharmaceuticals shelved its oral obesity drug after Phase 2 data missed every mark that matters

Late-breaking cardiovascular drug trials took center stage at ACC.25 Progress in the world of cardiovascular pharmacology made headlines at ACC.25, the annual meeting of the American College of Cardiology (ACC), with late-breaking trials unveiling new therapies, repurposed medications and promising advancements in long-standing treatment gaps

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The NOS evaluates studies based on three criteria: (1) selection of study groups (representativeness, ascertainment of exposure, and demonstration that the outcome was not present at baseline), (2) comparability of groups (control for confounding factors), and (3) assessment of outcome (adequacy of follow-up and blinding of outcome assessment)