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Additionally, a fraction of circulating iron exists as non-transferrin-bound iron (NTBI), which must first be reduced from Fe 3+ back to Fe 2+ by cell surface reductases before it can be transported across the plasma membrane through the combined action of the DMT1 and Zrt- and Irt-like Protein 14 (ZIP14) metal ion transporters

The optimal production of H 2 S 2 was achieved in the presence of 10 M cysteine with 100 M GSH, and that of H 2 S 3 in the presence of 1 M cysteine with 10 M GSH or in the absence of cysteine and GSH (Supplementary Fig

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Secondly, the side effects remain another challenge to improve the antitumor efficacy of drugs targeting glutamine metabolism

doi: 10.1089/ten.teb.2014.0188 81 BeattieGMMontgomeryAMLopezADHaoEPerezBJustML

An overview of ferroptosis in non-alcoholic fatty liver disease