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Additionally, ETS1, a key regulator of epithelial-mesenchymal transition (EMT) and metastasis in ovarian cancer cells, is also modulated by Gln

Locally born olfactory bulb stem cells proliferate in response to insulin-related factors and require endogenous insulin-like growth factor-I for differentiation into neurons and glia

The stroke-induced blood-brain barrier disruption: current progress of inspection technique, mechanism, and therapeutic target

The zebrafish ( Danio rerio ) model, with its unique attributes of optical transparency, genetic tractability, and high-throughput capability, has emerged as a transformative platform to address this bottleneck

At the same time, genetic engineering tools such as CRISPR/Cas9 enable the development of stress-resistant plant varieties tailored for compatibility with nanomaterials, improving delivery efficiency and overall efficacy (Rani et al., 2025)

We next performed a structural similarity search across our in-house compound collection, as well as on commercial small-molecule libraries (1,000,000 compounds) and identified 141 additional hits, which were screened in the high-throughput activity assay at a single concentration of 10 M