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In clinical trials of Tirzepatide, a dual-acting GLP-1 and GIP agonist currently prescribed for Type 2 diabetes, obese patients lost 21 percent body mass in 1.4 years, surpassing the 15 percent reduction seen with Semaglutide

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This was a landmark finding that established semaglutide as having direct nephroprotective properties

Research in this area has shown favourable results for fat-specific reduction

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