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University of Michigan

However, the difference was not statistically significant ( p = 0.07)

The release of cytochrome C from the mitochondria leads to production of a caspase-activating complex of cytochrome c, APAF-1, and procaspase-9, triggers the up-regulation of caspase-9, and subsequently increases the expression of caspase-3, followed by the induction of apoptotic events in the cell [44]

54 Radicular nerve pain One double-blind RCT amongst 64 patients with lower extremity radicular nerve pain compared the use of different doses of oral ALC (1180 mg/d versus 600 mg/d) with respect to total symptom score and EMG

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Sources: National Center for Complementary and Integrative Health (NCCIH) Turmeric and Curcumin This source provides research on the benefits of turmeric and curcumin in reducing inflammation and pain