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PD can affect the autonomic nervous system, leading to problems with blood pressure, heart rate, digestion, and bladder and bowel function, among other issues

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Regulatory T cells: masterminds of immune equilibrium and future therapeutic innovations

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doi: 10.1002/jat.3473

Over the following weeks most people notice steadier energy and fewer afternoon crashes first (weeks 12), then early fat loss around the midsection with workouts feeling more productive (weeks 24), then measurable body-fat reduction and better endurance and recovery (weeks 48), with metabolic markers like glucose and triglycerides often improving by week 8+