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Even if, in the first couple years of Mounjaro and Wegovy both being approved for the weight loss indication, the impact from just those taking it who can afford it/have the insurance for it can be significant
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Survival trends from the PraderWilli syndrome association (USA) 40-year mortality survey

Scientists have linked the medications, called GLP-1 receptor agonists, to increased survival in cancer patients and a reduction in obesity-related cancers

This is a genuinely clinical evidence base but it is phase-2/phase-3 investigational data, not a finished, approved product
Most participants taking the 25 mg Wegovy pill did experience side effects, which were typically mild
Their effect on mental health is a growing concern
