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Statements Author contributions GG: Writing original draft

doi: 10.15171/apb.2018.021

doi: 10.3390/molecules27207088 5 ZengCLinJZhangKOuHShenKLiuQet al

Mitochondria-targeted drugs induce tumor mtDNA oxidation and specific release into the cytoplasm, activating the cGAS-STING pathway and affecting tumor immune-related responses

However, it has also been reported that the PPP flux decrease may be an early event in the pathogenesis of sporadic PD, because in the later stages of PD, PPP flux is up-regulated in an attempt to counteract persistent oxidative stress [117]

The use of long-acting aripiprazole in a multi-center, prospective, uncontrolled, open-label, cohort study in Germany: a report on global assessment of functioning and the WHO wellbeing index