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Considering that the physiological concentration of succinate is in the M range it does not seem that reverse electron transfer from Complex II to Complex I is a significant physiological source of mitochondrial ROS (Mailloux and Harper, 2011)

(2018) 23:45869.e5

The cell biology of intervertebral disc aging and degeneration

The discontinuous arrows and dashed-line circles represent not-well established pathways

the maximal effect was measured at a concentration level of 1 mM Mg 2+ (Fig

Since the medicine enters directly into the bloodstream in the injection form, it is absorbed quickly and works much better than oral forms of the medicine