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Glutathione has attracted worldwide attention because of its central role in protecting cells from oxidative stress

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10.1016/S0304-3940(02)00144-1 7 BelyaevaE

These results suggest that HSF-1 plays a critical role in the cellular response to ER stress

However, during cancer progression, the accumulation of inducible nitric oxide synthase positive (iNOS+) and CD11b+Gr1+ myeloid cells in the peritumoral region suppresses the contraction of tumor-draining collecting lymphatic vessels (117) ( Figure 1 ), which might diminish tumor antigen transportation and DC trafficking to the TDLNs, reducing the immune response (118)

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